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The most accurate predictive report on technology and the global economy,

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by Edward Arvisais     Who's Coming to FiRe 2014?   Chris Lewicki first pioneer in Space Mining President & CHIEF ENGINEER, Planetary Resources       May 20-23     Montage Laguna Beach, CA                        To register, go to:            www.futureinreview.com     And many more, including: Mark Hurd, Oracle; Michael Dell, Dell Inc.; Author Neal Stephenson; Gary Shapiro,CEA/CES; Ken Goldman, Yahoo!; Jon Myers, Graphene Technologies; Geralyn Dreyfous, Impact Partners Film Fund; Leroy Hood, Institute for Systems Biology; Tom Taylor,Verizon; Vint Cerf, Google; Hugh Bradlow, Telstra; Barry Briggs, Microsoft; Marty Tenenbaum, Cancer Commons   See All Speakers & other Participants: www.futureinreview.com/participants FiRe Agenda: www.futureinreview.com/agenda

In This Issue     Feature: Special Letter   Decoding DNA: The Other 97%, in Real Time     The Historic Standard The Four Bases of DNA "Transcription" and "Translation": Reading DNA and RNA Epigenetics Genomics, Non-Coding Portions, and Cancer The Influence, and Limitations, of Sanger Sequencing Current Limits A Bacteria-Derived Polymerase: "A Puzzle in Which All Pieces Are Square" The Importance of the Non-Coding Protein Region Enter Exonucleases Adaptation to Direct Sequencing of RNA Looking Beyond the Exome About Edward Arvisais   Upcoming SNS Events & Media Links   In Other House News... How to Subscribe May I Share This Newsletter? About SNS About the Publisher Where's Mark?

 

Publisher's Note:

 

This week's issue is an absolute Must Read for anyone interested in the future of genetics, healthcare, biomedicine, and related issues. If you need to understand how DNA works, and - more important from a pragmatic perspective - how our current techniques fail to reveal real DNA sequences, and how to fix the problem, read on.

 

SNS members are aware that we long ago warned about the use of the term "junk" DNA: nature, in its evolutionary cloak, abhors not only a vacuum, but also any waste in energy or structure. This week's issue will help members understand why all base pairs should be considered to have been conserved for a purpose, and how important it is to read them - and How to read them.

 

We are now leaving the first- and second- generation worlds of genetic decoding, when we all picked the low-hanging fruit and just ignored the rest. Thanks to companies like NorthShore Bio, a company we are proud to have as a FiReStarter Company this year, we are now going to go back, go deeper, and get the real story, the whole story, the complete read of our genetic codes. - mra.